发明授权
US07670788B2 Determining and reducing immunoresistance to a Botulinum toxin therapy using Botulinum toxin B peptides
有权
使用肉毒杆菌毒素B肽确定和降低对肉毒杆菌毒素治疗的免疫耐受性
- 专利标题： Determining and reducing immunoresistance to a Botulinum toxin therapy using Botulinum toxin B peptides
- 专利标题（中）： 使用肉毒杆菌毒素B肽确定和降低对肉毒杆菌毒素治疗的免疫耐受性
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申请号： US12061952申请日： 2008-04-03
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公开(公告)号： US07670788B2公开(公告)日： 2010-03-02
- 发明人: M. Zouhair Atassi
- 申请人： M. Zouhair Atassi
- 申请人地址： US CA Irvine US TX Houston
- 专利权人： Allergan, Inc.,Baylor College of Medicine
- 当前专利权人： Allergan, Inc.,Baylor College of Medicine
- 当前专利权人地址： US CA Irvine US TX Houston
- 代理机构： Allergan, Inc.
- 代理商 Dean G. Stathakis; Joel B. German
- 主分类号： G01N33/53
- IPC分类号： G01N33/53
摘要：
The present invention provides BoNT/B peptides, BoNT/B peptide compositions, tolerogizing compositions, immune response inducing compositions, as well as methods of determining immunoresistance to botulinum toxin therapy in an individual, methods of treating immunoresistance to botulinum toxin therapy in an individual, methods of reducing anti-botulinum toxin antibodies in an individual and methods of inducing a BoNT/B immune response an individual.
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