发明授权
US07670800B2 Process for the purification of riboflavin 有权
核黄素纯化方法

  • 专利标题: Process for the purification of riboflavin
  • 专利标题(中): 核黄素纯化方法
  • 申请号: US10565443
    申请日: 2004-07-20
  • 公开(公告)号: US07670800B2
    公开(公告)日: 2010-03-02
  • 发明人: Arnold Gloor
  • 申请人: Arnold Gloor
  • 申请人地址: NL Te Heerlen
  • 专利权人: DSM IP Assets B.V.
  • 当前专利权人: DSM IP Assets B.V.
  • 当前专利权人地址: NL Te Heerlen
  • 代理机构: Hoxie & Associates LLC
  • 优先权: EP03016512 20030722
  • 国际申请: PCT/EP2004/008097 WO 20040720
  • 国际公布: WO2005/014594 WO 20050217
  • 主分类号: C12P25/00
  • IPC分类号: C12P25/00
Process for the purification of riboflavin
摘要:
The invention relates to a process for the purification of riboflavin comprising the steps of (a) precipitating a first crystalline form of riboflavin, (b) isolating the first crystalline form of riboflavin, (c) transforming the first crystalline form of riboflavin into a second crystalline form of riboflavin under conditions that decompose diluted DNA, and (d) isolating the second crystalline form of riboflavin, provided that at ambient temperature the first crystalline form of riboflavin is thermodynamically less stable than the second crystalline form of riboflavin.
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