发明授权
US07671059B2 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-ones
有权
2-氨基-7,8-二氢-6H-吡啶并[4,3-d]嘧啶-5-酮
- 专利标题: 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-ones
- 专利标题(中): 2-氨基-7,8-二氢-6H-吡啶并[4,3-d]嘧啶-5-酮
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申请号: US11541462申请日: 2006-09-28
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公开(公告)号: US07671059B2公开(公告)日: 2010-03-02
- 发明人: Timothy D. Machajewski , Cynthia M. Shafer , Christopher McBride , William Antonios-McCrea , Brandon M. Doughan , Barry H. Levine , Yi Xia , Maureen McKenna , X. Michael Wang , Kris Mendenhall , Yasheen Zhou , Kristin Brinner , Zhenhai Gao , Daniel Poon , Paul Barsanti , Xiaodong Lin , Abran Costales , Alice Rico , Nathan Brammeier , Teresa Pick , Paul A. Renhowe
- 申请人: Timothy D. Machajewski , Cynthia M. Shafer , Christopher McBride , William Antonios-McCrea , Brandon M. Doughan , Barry H. Levine , Yi Xia , Maureen McKenna , X. Michael Wang , Kris Mendenhall , Yasheen Zhou , Kristin Brinner , Zhenhai Gao , Daniel Poon , Paul Barsanti , Xiaodong Lin , Abran Costales , Alice Rico , Nathan Brammeier , Teresa Pick , Paul A. Renhowe
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Vinit Kathardekar; Hugo Eng; Dennis Shelton
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K31/5355 ; C07D471/04 ; C07D487/04 ; C07D413/06 ; A61P35/00
摘要:
Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
公开/授权文献
- US20070123546A1 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-ones 公开/授权日:2007-05-31