发明授权
US07674792B2 5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one
失效
5（Z）-5-（6-喹喔啉亚甲基）-2- [2,6-二氯苯基]氨基] -1,3-噻唑-4（5H） - 酮
![5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one](/docs/US/2010-03-09/US07674792B2/abs.jpg.600x600.jpg)
- 专利标题： 5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one
- 专利标题（中）： 5（Z）-5-（6-喹喔啉亚甲基）-2- [2,6-二氯苯基]氨基] -1,3-噻唑-4（5H） - 酮
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申请号： US11726741申请日： 2007-03-22
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公开(公告)号： US07674792B2公开(公告)日： 2010-03-09
- 发明人: Kevin J. Duffy , Duke M. Fitch , Beth A. Norton
- 申请人： Kevin J. Duffy , Duke M. Fitch , Beth A. Norton
- 申请人地址： US PA Philadelphia
- 专利权人： GlaxoSmithKline LLC
- 当前专利权人： GlaxoSmithKline LLC
- 当前专利权人地址： US PA Philadelphia
- 代理商 Wayne J. Dustman; Edward R. Gimmi; Charles M. Kinzig
- 主分类号： A61K31/498
- IPC分类号： A61K31/498 ; C07D417/06
![5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one](/abs-image/US/2010/03/09/US07674792B2/abs.jpg.150x150.jpg)
摘要：
Invented is the compound (5Z)-5-(6-quinoxalinylmethylidene)-2-[(2,6 -dichlorophenyl)amino]-1,3-thiazol-4(5H)-one, and/or pharmaceutically acceptable salts, hydrates, solvates and pro-drugs thereof. Also invented are pharmaceutical compositions containing this compound, methods of preparing this compound and pharmaceutically acceptable salts, hydrates, solvates and pro-drugs thereof. Also invented are methods of using this compound as an inhibitor of hYAK3 proteins.