发明授权
- 专利标题： Fused bicycloheterocycle substituted quinuclidine derivatives
- 专利标题（中）： 稠合双环杂环取代的奎宁环衍生物
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申请号： US11599651申请日： 2006-11-15
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公开(公告)号： US07674794B2公开(公告)日： 2010-03-09
- 发明人: Jianguo Ji , Tao Li
- 申请人： Jianguo Ji , Tao Li
- 申请人地址： US IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： US IL Abbott Park
- 代理商 Portia Chen
- 主分类号： A61K31/4375
- IPC分类号： A61K31/4375 ; A61K31/55
摘要：
Compounds of formula (I) wherein n is 0, 1, or 2; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
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