Set forth is an electrophoretic display device including a display region between substrates, at least one of which is transparent, the display region including a multiplicity of pixels, wherein one or more of the pixels have three or more subpixels, the three or more subpixels being made up of individual reservoirs that each contain a display medium of one or more set of colored particles in a dielectric fluid. The display mediums include two different colors therein so that the subpixel is capable of exhibiting each of the two different colors, and each of the three or more subpixels include a display medium having a combination of two colors that is different from the combinations of two colors of the display mediums of the other of the three or more subpixels. A method of displaying a full color image with the display device is also provided.