发明授权
US07678560B2 Δ 5 desaturase and its use in making polyunsaturated fatty acids
有权
＆Dgr 5去饱和酶及其在制备多不饱和脂肪酸中的应用
- 专利标题： Δ 5 desaturase and its use in making polyunsaturated fatty acids
- 专利标题（中）： ＆Dgr 5去饱和酶及其在制备多不饱和脂肪酸中的应用
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申请号： US11748629申请日： 2007-05-15
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公开(公告)号： US07678560B2公开(公告)日： 2010-03-16
- 发明人: Howard Glenn Damude , Dana M. Walters Pollak , Zhixiong Xue , Quinn Qun Zhu
- 申请人： Howard Glenn Damude , Dana M. Walters Pollak , Zhixiong Xue , Quinn Qun Zhu
- 申请人地址： US DE Wilmington
- 专利权人： E.I. du Pont de Nemours and Company
- 当前专利权人： E.I. du Pont de Nemours and Company
- 当前专利权人地址： US DE Wilmington
- 代理商 Lynne M. Christenbury
- 主分类号： C12N1/00
- IPC分类号： C12N1/00 ; C12N15/74 ; C07H21/04
摘要：
The present invention relates to a Δ5 desaturase, which has the ability to convert dihomo-γ-linolenic acid (DGLA; 20:3 ω-6) to arachidonic acid (ARA; 20:4 ω-6) and/or eicosatetraenoic acid (ETA; 20:4 ω-3) to eicosapentaenoic acid (EPA; 20:5 ω-3). Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ5 desaturase along with a method of making long chain polyunsaturated fatty acids (PUFAs) using this Δ5 desaturase in oleaginous yeast are disclosed.
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