- 专利标题: Quinazolines useful as modulators of ion channels
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申请号: US10792688申请日: 2004-03-03
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公开(公告)号: US07678802B2公开(公告)日: 2010-03-16
- 发明人: Jesus E. Gonzalez, III , Dean Mitchell Wilson , Andreas Peter Termin , Peter Diederik Jan Grootenhuis , Yulian Zhang , Benjamin John Petzoldt , Lev Tyler Dewey Fanning , Timothy Donald Neubert , Roger Tung , Esther Martinborough , Nicole Zimmerman
- 申请人: Jesus E. Gonzalez, III , Dean Mitchell Wilson , Andreas Peter Termin , Peter Diederik Jan Grootenhuis , Yulian Zhang , Benjamin John Petzoldt , Lev Tyler Dewey Fanning , Timothy Donald Neubert , Roger Tung , Esther Martinborough , Nicole Zimmerman
- 申请人地址: US MA Cambridge
- 专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人地址: US MA Cambridge
- 代理商 Michael C. Badia
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/12 ; C07D403/14 ; A61K31/517 ; C07D417/04 ; C07D417/12 ; C07D417/14 ; C07D409/04 ; C07D405/12 ; C07D413/12 ; A61K31/5377 ; A61P35/00
摘要:
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
公开/授权文献
- US20040248890A1 Quinazolines useful as modulators of ion channels 公开/授权日:2004-12-09