A medical implement dispenser and disposal system is provided. The medical implement dispenser and disposal system comprises an enclosure having a body portion. A dispensing chamber within the body portion is configured to contain medical implements. A collection chamber within the body portion above the dispensing chamber is configured to collect soiled medical implements. The body portion defines an access opening positioned for passage of medical implements from the dispensing chamber and an inlet opening positioned for passage of soiled medical implements into the collection chamber, wherein the access opening is oriented in a forward facing direction and the inlet opening is also oriented in the forward facing direction. A barrier is positioned within the body portion to separate the dispensing chamber from the collection chamber. The barrier limits the passage of soiled medical implements from the collection chamber to the dispensing chamber.