发明授权
- 专利标题: Synthesis and crystalline forms of NPY5 antagonist
- 专利标题(中): NPY5拮抗剂的合成和结晶形式
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申请号: US11988780申请日: 2006-07-24
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公开(公告)号: US07700611B2公开(公告)日: 2010-04-20
- 发明人: Russell R. Ferlita , Yuji Haga , Makoto Ishikawa , Keisuke Kamei , Shinji Kato , Hisaki Kojima , Aaron Moment , Nobuaki Nonoyama , Nobuya Satake , Kazuki Shigemori , Toshihiro Wada , Yaling Wang , Steven A. Weissman , Robert M. Wenslow
- 申请人: Russell R. Ferlita , Yuji Haga , Makoto Ishikawa , Keisuke Kamei , Shinji Kato , Hisaki Kojima , Aaron Moment , Nobuaki Nonoyama , Nobuya Satake , Kazuki Shigemori , Toshihiro Wada , Yaling Wang , Steven A. Weissman , Robert M. Wenslow
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Baerbel R. Brown; John C. Todaro
- 国际申请: PCT/US2006/028650 WO 20060724
- 国际公布: WO2007/016028 WO 20070208
- 主分类号: A61K31/4355
- IPC分类号: A61K31/4355 ; C07D491/048
摘要:
The present invention relates to a process for producing crystalline trans-N-[1-(2-fluorophenyl)-S-pyrazoly]-3-ox-ospiro[6-azaisobenzofuran-1(3H),1′-cyclohexane]-4′-carboxamide and novel salts, hydrates and polymorphs thereof.
公开/授权文献
- US20090124648A1 Synthesis and Crystalline Forms of Npy5 Antagonist 公开/授权日:2009-05-14