发明授权
- 专利标题： Inhibitors of AKT activity
- 专利标题（中）： AKT活性抑制剂
-
申请号： US11918386申请日： 2006-04-10
-
公开(公告)号： US07705014B2公开(公告)日： 2010-04-27
- 发明人: Chixu Chen , Brian W. Eastman , Essa H. Hu
- 申请人： Chixu Chen , Brian W. Eastman , Essa H. Hu
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Matthew A. Leff; David A. Muthard
- 国际申请： PCT/US2006/013280 WO 20060410
- 国际公布： WO2006/110638 WO 20061019
- 主分类号： C07D513/02
- IPC分类号： C07D513/02 ; C07D515/02 ; A01N43/42 ; A61K31/44
摘要：
The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
公开/授权文献
- US20090062327A1 Inhibitors of AKT Activity 公开/授权日：2009-03-05