发明授权
- 专利标题: Histamine H3 receptor agents, preparation and therapeutic uses
- 专利标题(中): 组胺H3受体剂,制剂及治疗用途
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申请号: US11574044申请日: 2005-08-15
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公开(公告)号: US07705025B2公开(公告)日: 2010-04-27
- 发明人: Don Richard Finley , Terry Patrick Finn , Philip Arthur Hipskind , William Joseph Hornback , Cynthia Darshini Jesudason , Takako Takakuwa
- 申请人: Don Richard Finley , Terry Patrick Finn , Philip Arthur Hipskind , William Joseph Hornback , Cynthia Darshini Jesudason , Takako Takakuwa
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 Dan L. Wood
- 国际申请: PCT/US2005/029032 WO 20050815
- 国际公布: WO2006/023462 WO 20060302
- 主分类号: A61K31/427
- IPC分类号: A61K31/427 ; C07D277/20
摘要:
The present invention provides a novel compound of Formula (I) or a pharmaceutically acceptable salt thereof, having histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another, embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
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