发明授权
- 专利标题： ActRII receptor polypeptides, methods and compositions
- 专利标题（中）： ActRII受体多肽，方法和组合物
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申请号： US11190202申请日： 2005-07-25
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公开(公告)号： US07709605B2公开(公告)日： 2010-05-04
- 发明人: John Knopf , Jasbir Seehra
- 申请人： John Knopf , Jasbir Seehra
- 申请人地址： US MA Cambridge
- 专利权人： Acceleron Pharma Inc.
- 当前专利权人： Acceleron Pharma Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Ropes & Gray LLP
- 主分类号： C07K14/00
- IPC分类号： C07K14/00
摘要：
In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, and/or neuron. The present invention also provides methods of screening compounds that modulate activity of an ActRII protein and/or an ActRII ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRII protein and/or an ActRII ligand.
公开/授权文献
- US20060068468A1 ActRII receptor polypeptides, methods and compositions 公开/授权日：2006-03-30
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