发明授权
- 专利标题： Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof
- 专利标题（中）： 含氮杂环化合物及其制备含氮杂环化合物的方法及其中间体
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申请号： US11313289申请日： 2005-12-19
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公开(公告)号： US07709640B2公开(公告)日： 2010-05-04
- 发明人: James Kanter , Anjali Pandey , James Robinson , Robert M. Scarborough
- 申请人： James Kanter , Anjali Pandey , James Robinson , Robert M. Scarborough
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Townsend and Townsend and Crew, LLP
- 主分类号： C07D295/182
- IPC分类号： C07D295/182
摘要：
The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.
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