发明授权
US07713977B2 (1-aza-bicyclo[3.3.1]non-4-yl)-[5-(1H-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders
有权
（1-氮杂 - 双环[3.3.1]壬-4-基） - [5-（1H-吲哚-5-基） - 杂芳基] - 胺作为用于治疗精神病和神经变性的n-ach的胆碱能配体 疾病
![(1-aza-bicyclo[3.3.1]non-4-yl)-[5-(1H-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders](/docs/US/2010-05-11/US07713977B2/abs.jpg.600x600.jpg)
- 专利标题： (1-aza-bicyclo[3.3.1]non-4-yl)-[5-(1H-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders
- 专利标题（中）： （1-氮杂 - 双环[3.3.1]壬-4-基） - [5-（1H-吲哚-5-基） - 杂芳基] - 胺作为用于治疗精神病和神经变性的n-ach的胆碱能配体 疾病
-
申请号： US12097689申请日： 2006-12-14
-
公开(公告)号： US07713977B2公开(公告)日： 2010-05-11
- 发明人: Dominik Feuerbach , Mathias Frederiksen , Konstanze Hurth , Bernard Lucien Roy , Manuel Koller
- 申请人： Dominik Feuerbach , Mathias Frederiksen , Konstanze Hurth , Bernard Lucien Roy , Manuel Koller
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理机构： Fanelli Strain & Haag PLLC
- 代理商 Paul D. Strain, Esq.
- 优先权： GB0525673.0 20051216
- 国际申请： PCT/EP2006/012022 WO 20061214
- 国际公布： WO2007/068475 WO 20070621
- 主分类号： C07D471/08
- IPC分类号： C07D471/08 ; A61K31/439
![(1-aza-bicyclo[3.3.1]non-4-yl)-[5-(1H-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders](/abs-image/US/2010/05/11/US07713977B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5 R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: in free base or acid addition salt form, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
公开/授权文献
- US20080262030A1 Organic Compounds 公开/授权日：2008-10-23
信息查询
