发明授权
- 专利标题: Medical devices with associated growth factors
- 专利标题(中): 具有相关生长因子的医疗器械
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申请号: US09186810申请日: 1998-11-05
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公开(公告)号: US07722671B1公开(公告)日: 2010-05-25
- 发明人: Wenda C. Carlyle , Sheila J. Kelly , Matthew F. Ogle
- 申请人: Wenda C. Carlyle , Sheila J. Kelly , Matthew F. Ogle
- 申请人地址: US MN St. Paul
- 专利权人: St. Jude Medical, Inc.
- 当前专利权人: St. Jude Medical, Inc.
- 当前专利权人地址: US MN St. Paul
- 代理机构: Westman, Champlin & Kelly, P.A.
- 代理商 Hallie A. Finucane
- 主分类号: A61F2/02
- IPC分类号: A61F2/02
摘要:
A polypeptide growth factor is associated with a substrate to promote population of the substrate with endothelial cells. In a preferred approach, the growth factor is associated with the substrate by crosslinking under suitably mild conditions such that the growth factor is active following the crosslinking process. Thus, a prosthesis is formed with growth factor crosslinked to the substrate.
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