The present invention provides a multi-piece solid golf ball having a core, an envelope layer encasing the core, an intermediate layer encasing the envelope layer, and a cover which encases the intermediate layer and has formed on a surface thereof a plurality of dimples. The core is formed primarily of a rubber material, the envelope layer and the intermediate layer are each formed primarily of the same or different resin materials, and the cover is formed primarily of a thermoplastic resin or a thermoplastic elastomer. The envelope layer, intermediate layer and cover have thicknesses which satisfy the condition: cover thickness cover material hardness. The golf ball has an outstanding flight performance and controllability which are acceptable to professionals and other skilled players, in addition to which it has an excellent durability to cracking under repeated impact and an excellent scuff resistance.