发明授权
- 专利标题： Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome
- 专利标题（中）： 联合治疗急性白血病和骨髓增生异常综合征
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申请号： US11811626申请日： 2007-06-11
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公开(公告)号： US07727968B2公开(公告)日： 2010-06-01
- 发明人: Jay Marshall Feingold , Matthew L. Sherman , Lance H. Leopold , Mark Berger
- 申请人： Jay Marshall Feingold , Matthew L. Sherman , Lance H. Leopold , Mark Berger
- 申请人地址： US NJ Madison
- 专利权人： Wyeth LLC
- 当前专利权人： Wyeth LLC
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/70
- IPC分类号： A61K31/70
摘要：
Methods of treatment and pharmaceutical combinations are provided for the treatment of acute leukemia, such as acute myelogenous leukemia, and myelodysplastic syndrome. The methods of treatment and pharmaceutical combinations employ an anti-CD33 cytotoxic conjugate in combination with at least one compound selected from the group consisting of an anthracycline and a pyrimidine or purine nucleoside analog. Preferred methods of treatment and pharmaceutical combinations employ gemtuzumab ozogamicin, daunorubicin, and cytarabine.
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