发明授权
- 专利标题： N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
- 专利标题（中）： N，N'-取代-1,3-二氨基-2-羟基丙烷衍生物
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申请号： US11636903申请日： 2006-12-11
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公开(公告)号： US07727997B2公开(公告)日： 2010-06-01
- 发明人: Varghese John , Michel Maillard , Barbara Jagodzinska , James Beck , Andrea Gailunas , John Freskos , John Mickelson , Lakshman Samala , Jennifer Sealey , Ruth Tenbrink , Larry Fang , Roy Hom
- 申请人： Varghese John , Michel Maillard , Barbara Jagodzinska , James Beck , Andrea Gailunas , John Freskos , John Mickelson , Lakshman Samala , Jennifer Sealey , Ruth Tenbrink , Larry Fang , Roy Hom
- 申请人地址： US CA So. San Francisco
- 专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人地址： US CA So. San Francisco
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： A61K31/133
- IPC分类号： A61K31/133 ; C07D217/00
摘要：
Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of disorders such as Alzheimer's Disease.
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