A wireless communication device includes an integrated circuit (IC) and an antenna system. The IC includes a baseband processing module, a network processing module, a calibration processing module, a receiver section and a transmitter section. The network processing module establishes a wireless communication protocol and operational parameters based on the wireless communication protocol. The calibration processing module generates RF receiver calibration information based on the operational parameters and RF receive feedback and generates RF transmitter calibration information based on the operational parameters and RF transmit feedback. The receiver section provides the RF receive feedback and converts an inbound RF signal into an inbound symbol stream. The transmitter section provides the RF transmit feedback and converts an outbound symbol stream into an outbound RF signal. The antenna system provides the inbound RF signal to the receiver section and receives the outbound RF signal from the transmitter section.