发明授权
US07732432B2 17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators
失效
17-氨甲酰氧基皮质醇衍生物作为选择性糖皮质激素受体调节剂
- 专利标题： 17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators
- 专利标题（中）： 17-氨甲酰氧基皮质醇衍生物作为选择性糖皮质激素受体调节剂
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申请号： US10540757申请日： 2004-01-16
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公开(公告)号： US07732432B2公开(公告)日： 2010-06-08
- 发明人: Amjad Ali , James M. Balkovec , Donald W. Graham , Mark L. Greenlee , Gayle E. Taylor
- 申请人： Amjad Ali , James M. Balkovec , Donald W. Graham , Mark L. Greenlee , Gayle E. Taylor
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Yong Zhao; Valerie J. Camara
- 国际申请： PCT/US2004/001191 WO 20040116
- 国际公布： WO2004/066920 WO 20040812
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; C07J5/00
摘要：
The present invention encompasses compounds of Formula (I) or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.
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