发明授权
US07732453B2 Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors
失效
用作硬脂酰辅酶A去饱和酶抑制剂的吡啶并[2,3-B]吡嗪-3（4H） - 酮
![Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors](/docs/US/2010-06-08/US07732453B2/abs.jpg.600x600.jpg)
- 专利标题： Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors
- 专利标题（中）： 用作硬脂酰辅酶A去饱和酶抑制剂的吡啶并[2,3-B]吡嗪-3（4H） - 酮
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申请号： US11868386申请日： 2007-10-05
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公开(公告)号： US07732453B2公开(公告)日： 2010-06-08
- 发明人: Dmitry Koltun , Jeff Zablocki , Eric Parkhill , Andrey Glushkov , Natalya Vasilevich , Timur Zilbershtein , Alexey Ivanov
- 申请人： Dmitry Koltun , Jeff Zablocki , Eric Parkhill , Andrey Glushkov , Natalya Vasilevich , Timur Zilbershtein , Alexey Ivanov
- 申请人地址： US CA Foster City
- 专利权人： Gilead Palo Alto, Inc.
- 当前专利权人： Gilead Palo Alto, Inc.
- 当前专利权人地址： US CA Foster City
- 代理商 J. Elin Hartrum
- 主分类号： A61K31/4965
- IPC分类号： A61K31/4965
![Pyrido[2,3-B] pyrazin-3(4H)-ones for use as stearoyl CoA desaturase inhibitors](/abs-image/US/2010/06/08/US07732453B2/abs.jpg.150x150.jpg)
摘要：
The present invention discloses pyrido[2,3-B]pyrazin-3(4h)-ones for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, oily skin conditions, metabolic syndrome, and the like.
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