发明授权
- 专利标题： Substituted benzimidazoles and methods of their use
- 专利标题（中）： 取代的苯并咪唑及其使用方法
-
申请号： US12315779申请日： 2008-12-05
-
公开(公告)号： US07732465B2公开(公告)日： 2010-06-08
- 发明人: Mina E. Aikawa , Payman Amiri , Jeffrey H. Dove , Barry Haskell Levine , Christopher McBride , Teresa E. Pick , Daniel J. Poon , Savithri Ramurthy , Paul A. Renhowe , Cynthia Shafer , Darrin Stuart , Sharadha Subramanian
- 申请人： Mina E. Aikawa , Payman Amiri , Jeffrey H. Dove , Barry Haskell Levine , Christopher McBride , Teresa E. Pick , Daniel J. Poon , Savithri Ramurthy , Paul A. Renhowe , Cynthia Shafer , Darrin Stuart , Sharadha Subramanian
- 申请人地址： US CA Emeryville
- 专利权人： Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人： Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人地址： US CA Emeryville
- 代理机构： Swiss Tanner, P.C.
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439
摘要：
New substituted benzimidazole compounds, compositions, and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer.
公开/授权文献
- US20090170904A1 Substituted benzimidazoles and methods of their use 公开/授权日：2009-07-02