Multi-transmitter interference caused by one or more interfering own-cell and/or other-cell transmitters is reduced in a RAKE-based receiver. The RAKE-based receiver comprises a plurality of RAKE fingers, a processor and a combiner. The plurality of RAKE fingers are configured to despread received symbols, wherein a delay for a first one of the plurality of RAKE fingers corresponds to a symbol of interest transmitted by a first transmitter and a delay for a second one of the plurality of RAKE fingers corresponds to an interfering symbol transmitted by a second transmitter. The processor is configured to determine a cross-correlation between the symbol of interest and the interfering symbol. The combiner is configured to combine the symbol of interest with the interfering symbol using the cross-correlation to reduce interference attributable to the interfering symbol from the symbol of interest.