发明授权
US07745447B2 Substituted thieno[3,2-D]pyrimidines as non-basic melanin concentrating hormone receptor-1 antagonists
有权
取代的噻吩并[3,2-D]嘧啶作为非碱性黑色素浓缩激素受体-1拮抗剂
- 专利标题: Substituted thieno[3,2-D]pyrimidines as non-basic melanin concentrating hormone receptor-1 antagonists
- 专利标题(中): 取代的噻吩并[3,2-D]嘧啶作为非碱性黑色素浓缩激素受体-1拮抗剂
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申请号: US11586147申请日: 2006-10-25
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公开(公告)号: US07745447B2公开(公告)日: 2010-06-29
- 发明人: William N. Washburn , Saleem Ahmad , Khehyong Ngu
- 申请人: William N. Washburn , Saleem Ahmad , Khehyong Ngu
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 代理商 Maureen S. Gibbons
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K31/519 ; A61P25/22 ; A61P3/04 ; A61P3/10
摘要:
The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I.
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