发明授权
- 专利标题： Mitotic kinesin inhibitors
- 专利标题（中）： 有丝分裂驱动蛋白抑制剂
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申请号： US10506702申请日： 2003-03-04
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公开(公告)号： US07745639B2公开(公告)日： 2010-06-29
- 发明人: Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , J. Christopher Culberson , George D. Hartman , Brenda J. Mariano , Maricel Torrent
- 申请人： Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , J. Christopher Culberson , George D. Hartman , Brenda J. Mariano , Maricel Torrent
- 申请人地址： US NJ Rahway US NJ Rahway
- 专利权人： Merck & Co., Inc.,Merck Sharp & Dohme Corp.
- 当前专利权人： Merck & Co., Inc.,Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway US NJ Rahway
- 代理商 Nicole M. Beeler; David A. Muthard
- 国际申请： PCT/US03/06403 WO 20030304
- 国际公布： WO03/079973 WO 20031002
- 主分类号： C07D231/06
- IPC分类号： C07D231/06 ; A01N43/56
摘要：
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- US20050119484A1 Mitotic kinesin inhibitors 公开/授权日：2005-06-02
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