发明授权
- 专利标题: Method for treating severe heart failure and medicament therefor
- 专利标题(中): 治疗严重心力衰竭的方法及其药物
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申请号: US12149578申请日: 2008-05-05
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公开(公告)号: US07749993B2公开(公告)日: 2010-07-06
- 发明人: Atsushi Ozaki , Yôsuke Maki , Osamu Sato , Yoshitaka Yamamura
- 申请人: Atsushi Ozaki , Yôsuke Maki , Osamu Sato , Yoshitaka Yamamura
- 申请人地址: JP Tokyo
- 专利权人: Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人: Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 主分类号: A61K31/55
- IPC分类号: A61K31/55
摘要:
A method for treating severe heart failure, comprising administering to a patient an effective amount of a benzazepine compound (1): wherein R1 is H or halogen, R2 is OH, or —NR5R6 (R5 and R6 are H or lower alkyl, R3 is H, halogen, lower alkyl, or lower alkoxy, R4 is halogen, lower alkyl or lower alkoxy, or a salt thereof, and a pharmaceutical composition containing the benzazepine compound (1) or a salt thereof and use of the compound (1) or a salt thereof for preparing a medicament for treatment of severe heart failure.
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