发明授权
- 专利标题： Pentacyclic kinase inhibitors
- 专利标题（中）： 五环激酶抑制剂
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申请号： US11503405申请日： 2006-08-14
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公开(公告)号： US07749994B2公开(公告)日： 2010-07-06
- 发明人: Thomas E. Rawson , Brian Safina , Jennafer Dotson , Aihe Zhou , Ignacio Aliagas-Martin , Jason Halladay , Jun Liang , Matthias Rueth , Bing-Yan Zhu , Frederick Brookfield , Michael Prime , Birong Zhang , Jun M. Li
- 申请人： Thomas E. Rawson , Brian Safina , Jennafer Dotson , Aihe Zhou , Ignacio Aliagas-Martin , Jason Halladay , Jun Liang , Matthias Rueth , Bing-Yan Zhu , Frederick Brookfield , Michael Prime , Birong Zhang , Jun M. Li
- 申请人地址： US CA South San Francisco US NJ Nutley CH Basel
- 专利权人： Genentech, Inc.,Hoffman-LaRoche, Inc. (US Only),F. Hoffman-LaRoche, AG (EX-US)
- 当前专利权人： Genentech, Inc.,Hoffman-LaRoche, Inc. (US Only),F. Hoffman-LaRoche, AG (EX-US)
- 当前专利权人地址： US CA South San Francisco US NJ Nutley CH Basel
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/538 ; A61K31/424 ; A61K31/4188 ; C07D498/22
摘要：
The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula I wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2, R3 and m are defined herein.
公开/授权文献
- US20070037791A1 Pentacyclic kinase inhibitors 公开/授权日：2007-02-15
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