发明授权
- 专利标题： Quinuclidine derivatives and their pharmaceutical use
- 专利标题（中）： 奎宁环衍生物及其药物用途
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申请号： US10568148申请日： 2004-06-29
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公开(公告)号： US07750022B2公开(公告)日： 2010-07-06
- 发明人: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Philip K. Ahring , Tino Dyhring Jørgensen , Michael R. Schrimpf , Kevin B. Sippy
- 申请人： Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Philip K. Ahring , Tino Dyhring Jørgensen , Michael R. Schrimpf , Kevin B. Sippy
- 申请人地址： DK Ballerup US IL Abbott Park
- 专利权人： Neurosearch A/S,Abbott Laboratories
- 当前专利权人： Neurosearch A/S,Abbott Laboratories
- 当前专利权人地址： DK Ballerup US IL Abbott Park
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP.
- 优先权： WOPCT/DK03/00538 20030813
- 国际申请： PCT/EP2004/051283 WO 20040629
- 国际公布： WO2005/016923 WO 20050224
- 主分类号： A61K31/4745
- IPC分类号： A61K31/4745 ; C07D453/02
摘要：
This invention relates to novel quinuclidine derivatives and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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