发明授权
- 专利标题: Modulation of apolipoprotein c-III expression
- 专利标题(中): 载脂蛋白c-III表达的调节
-
申请号: US10553722申请日: 2004-04-15
-
公开(公告)号: US07750141B2公开(公告)日: 2010-07-06
- 发明人: Rosanne M. Crooke , Mark J. Graham , Kenneth W. Dobie
- 申请人: Rosanne M. Crooke , Mark J. Graham , Kenneth W. Dobie
- 申请人地址: US CA Carlsbad
- 专利权人: Isis Pharmaceuticals, Inc.
- 当前专利权人: Isis Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Carlsbad
- 代理机构: Isis Pharmaceuticals, Inc. Patent Dept.
- 国际申请: PCT/US2004/010946 WO 20040415
- 国际公布: WO2004/093783 WO 20041104
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C07H21/04
摘要:
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided.
公开/授权文献
- US20060264395A1 Modulation of apolipoprotein c-III expression 公开/授权日:2006-11-23
信息查询