An exemplary voltage regulator module (VRM) control circuit includes a VRM providing a plurality of phases, each of the phases connected to a control terminal of a corresponding electric switch; a comparator comprising a non-inverting terminal connected to a first power source and grounded via the electric switches respectively, an inverting terminal connected to a reference voltage, and an output terminal; and a control switch connected between an enable terminal of the VRM and ground, the control switch comprising a control terminal connected to the output terminal of the comparator, wherein, if one of the phases of the VRM is lost, the corresponding electric switch is turned off, and a voltage of the non-inverting terminal of the comparator is higher than the reference voltage, the comparator outputs a control signal to the control switch for turning on the control switch, thus turning off the VRM.