发明授权
- 专利标题： Production and purification of IL-29
- 专利标题（中）： 生产和纯化IL-29
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申请号： US12537935申请日： 2009-08-07
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公开(公告)号： US07759092B2公开(公告)日： 2010-07-20
- 发明人: Bruce L. Zamost , Robert M. Dedinsky
- 申请人： Bruce L. Zamost , Robert M. Dedinsky
- 申请人地址： US TN Nashville
- 专利权人： ZymoGenetics, LLC
- 当前专利权人： ZymoGenetics, LLC
- 当前专利权人地址： US TN Nashville
- 代理商 Brian J. Walsh
- 主分类号： C12N15/24
- IPC分类号： C12N15/24 ; C12P21/02
摘要：
The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
公开/授权文献
- US20100003722A1 PRODUCTION AND PURIFICATION OF IL-29 公开/授权日：2010-01-07
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