发明授权
- 专利标题： Soluble T cell receptors
- 专利标题（中）： 可溶性T细胞受体
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申请号： US11926391申请日： 2007-10-29
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公开(公告)号： US07763718B2公开(公告)日： 2010-07-27
- 发明人: Bent Karsten Jakobsen , Meir Glick
- 申请人： Bent Karsten Jakobsen , Meir Glick
- 申请人地址： GB
- 专利权人： Immunocore Limited
- 当前专利权人： Immunocore Limited
- 当前专利权人地址： GB
- 代理机构： Banner & Witcoff, Ltd.
- 优先权： GB0121187.9 20010831; GB0219146.8 20020816
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12P21/06 ; C12N1/20 ; C12N15/00
摘要：
The present invention provides a soluble T cell receptor (sTCR), which comprises (i) all or part of a TCR α chain, except the transmembrane domain thereof, and (ii) all or part of a TCR β chain, except the transmembrane domain thereof. (i) and (ii) each comprise a functional variable domain and at least a part of the constant domain of the TCR chain, and are linked by a disulphide bond between constant domain residues which is not present in native TCR.
公开/授权文献
- US20080153131A1 SOLUBLE T CELL RECEPTORS 公开/授权日：2008-06-26
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