Invention Grant
- Patent Title: Optimized relaxivity and specificity hepatobiliary MRI contrast agent
- Patent Title (中): 优化的松弛度和特异性肝胆管造影剂
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Application No.: US11601011Application Date: 2006-11-17
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Publication No.: US07767196B2Publication Date: 2010-08-03
- Inventor: Wing Tak Wong , Wai Yan Chan
- Applicant: Wing Tak Wong , Wai Yan Chan
- Applicant Address: HK Hong Kong
- Assignee: The University of Hong Kong
- Current Assignee: The University of Hong Kong
- Current Assignee Address: HK Hong Kong
- Agency: Cooper & Dunham LLP
- Agent Robert D. Katz
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K49/10
Abstract:
An adamantane functionalized magnetic resonance imaging (MRI) contrast agent has been synthesized, and shows high liver specificity, prolonged retention time in both the liver and kidneys, the highest relaxivity among clinical contrast agents, high water solubility, thermodynamic stability, signal intensity enhancement, hepatocellular uptake, and low osmolality and toxicity.
Public/Granted literature
- US20070116648A1 Optimized relaxivity and specificity hepatobiliary MRI contrast agent Public/Granted day:2007-05-24
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