Invention Grant
- Patent Title: Cultured hematopoietic stem cells and method for expansion and analysis thereof
- Patent Title (中): 培养造血干细胞及其扩增及分析方法
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Application No.: US11255191Application Date: 2005-10-20
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Publication No.: US07767453B2Publication Date: 2010-08-03
- Inventor: Chengcheng Zhang , Harvey Lodish
- Applicant: Chengcheng Zhang , Harvey Lodish
- Applicant Address: US MA Cambridge
- Assignee: Whitehead Institute for Biomedical Research
- Current Assignee: Whitehead Institute for Biomedical Research
- Current Assignee Address: US MA Cambridge
- Agency: Proskauer Rose LLP
- Main IPC: C12N5/00
- IPC: C12N5/00
Abstract:
Hematopoietic stem cells and methods for ex vivo expansion of hematopoietic stem cells are provided. The methods comprise culturing the cells in a media containing an effective amount insulin-like growth factor (IGF), fibroblast growth factor (FGF), thrombopoietin (TPO), and stem cell factor (SCF), under conditions sufficient for expansion of said cells. Methods for identifying expanded hematopoeitc stem cells and kits for ex vivo expansion of hematopoietic stem cells are also provided.
Public/Granted literature
- US20060115898A1 Cultured hematopoietic stem cells and method for expansion and analysis thereof Public/Granted day:2006-06-01
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