Invention Grant
US07767683B2 Hydrogen succinate salts of trans-4-((1R, 3S)-6-chloro-3-phenylindan-1-YL)-1,2,2-trimethylpiperazine and the use as a medicament
有权
反-4 - （（1R，3S）-6-氯-3-苯基茚-1-基）-1,2,2-三甲基哌嗪的琥珀酸琥珀酸盐和用作药物的用途
- Patent Title: Hydrogen succinate salts of trans-4-((1R, 3S)-6-chloro-3-phenylindan-1-YL)-1,2,2-trimethylpiperazine and the use as a medicament
- Patent Title (中): 反-4 - （（1R，3S）-6-氯-3-苯基茚-1-基）-1,2,2-三甲基哌嗪的琥珀酸琥珀酸盐和用作药物的用途
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Application No.: US10568572Application Date: 2004-08-18
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Publication No.: US07767683B2Publication Date: 2010-08-03
- Inventor: Heidi Lopez de Diego , Ole Nielsen , Lone Munch Ringgard , Henrik Svane , Allan Carsten Dahl , Mark Howells , Benny Bang-Andersen , Lars Ole Lyngso , Sherry Lynn Collier
- Applicant: Heidi Lopez de Diego , Ole Nielsen , Lone Munch Ringgard , Henrik Svane , Allan Carsten Dahl , Mark Howells , Benny Bang-Andersen , Lars Ole Lyngso , Sherry Lynn Collier
- Applicant Address: DK Valby-Copenhagen
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby-Copenhagen
- Agent Stephen G. Kalinchak; Margaret M. Buck
- Priority: DK200301180 20030818; DK200301305 20030911
- International Application: PCT/DK2004/000545 WO 20040818
- International Announcement: WO2005/016900 WO 20050224
- Main IPC: A61K31/495
- IPC: A61K31/495 ; C07D241/04
Abstract:
4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate, pharmaceutical compositions containing the salt and the medical use thereof, including for the treatment of schizophrenia and other psychotic disorders. Also described are methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and medical uses thereof.
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