Invention Grant
- Patent Title: Hsp90 family protein inhibitors
- Patent Title (中): Hsp90家族蛋白抑制剂
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Application No.: US12427847Application Date: 2009-04-22
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Publication No.: US07767693B2Publication Date: 2010-08-03
- Inventor: Shinji Nara , Hiroshi Nakagawa , Yutaka Kanda , Takayuki Nakashima , Shiro Soga , Jiro Kajita , Jun-ichi Saito , Yukimasa Shiotsu , Shiro Akinaga
- Applicant: Shinji Nara , Hiroshi Nakagawa , Yutaka Kanda , Takayuki Nakashima , Shiro Soga , Jiro Kajita , Jun-ichi Saito , Yukimasa Shiotsu , Shiro Akinaga
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Priority: JP2003-185475 20030627
- Main IPC: A01N43/40
- IPC: A01N43/40 ; C07D211/22 ; C07C49/303

Abstract:
The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; R1 represents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONR7R8 or the like; R2 represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; R3 and R5, which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and R4 and R6, which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.
Public/Granted literature
- US20090247522A1 Hsp90 FAMILY PROTEIN INHIBITORS Public/Granted day:2009-10-01
Information query
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