Invention Grant
- Patent Title: Pharmaceutical composition for oral administration
- Patent Title (中): 用于口服给药的药物组合物
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Application No.: US12305337Application Date: 2007-06-20
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Publication No.: US07767709B2Publication Date: 2010-08-03
- Inventor: Ales Franc , Petr Sova
- Applicant: Ales Franc , Petr Sova
- Applicant Address: CZ Brno
- Assignee: PLIVA-Lachema a.s.
- Current Assignee: PLIVA-Lachema a.s.
- Current Assignee Address: CZ Brno
- Agency: Notaro, Michalos & Zaccaria P.C.
- Priority: CZPV2006-402 20060620
- International Application: PCT/CZ2007/000058 WO 20070620
- International Announcement: WO2007/147371 WO 20071227
- Main IPC: A61K31/28
- IPC: A61K31/28

Abstract:
An oral pharmaceutical composition characterized in that it consists of a suspension of a platinum complex of general formula I, wherein A and A′ independently of one another are an NH3 group or an amino or diamino group containing 1 to 18 carbon atoms, B and B′ independently of one another are a halogen atom or a hydroxy group or are an —O—C(O)—R or an —O—C(O)—R′ group wherein R and R′ independently of one another are hydrogen atom, an alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy group which groups contain 1 to 10 carbon atoms, or functional derivatives of these groups, X and X′ independently of one another are a halogen atom or a monocarboxylate group containing 1 to 20 carbon atoms, or X and X′ together form a dicarboxylate group containing 2 to 20 carbon atoms, in at least one pharmaceutically acceptable vegetable, animal, mineral, synthetic or semisynthetic oil and/or in at least one pharmaceutically acceptable vegetable, animal, mineral, synthetic or semisynthetic oily substance, in which suspension the content of the platinum complex of general formula I is 0.5 to 50% by weight based on the total weight of the composition, and which suspension optionally contains at least one pharmaceutically acceptable excipient.
Public/Granted literature
- US20100010083A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION Public/Granted day:2010-01-14
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