Invention Grant
- Patent Title: Polyphenol proteasome inhibitors, synthesis, and methods of use
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Application No.: US11820799Application Date: 2007-06-20
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Publication No.: US07767711B2Publication Date: 2010-08-03
- Inventor: Q. Ping Dou , Tak-Hang Chan , David M. Smith
- Applicant: Q. Ping Dou , Tak-Hang Chan , David M. Smith
- Applicant Address: US FL Tampa CA HK Hong Kong
- Assignee: University of South Florida,McGill University,The Hong Kong Polytechnic University
- Current Assignee: University of South Florida,McGill University,The Hong Kong Polytechnic University
- Current Assignee Address: US FL Tampa CA HK Hong Kong
- Agency: Saliwanchik, Lloyd & Saliwanchik
- Main IPC: A01N37/10
- IPC: A01N37/10 ; A61K31/16

Abstract:
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.
Public/Granted literature
- US20080015248A1 Polyphenol proteasome inhibitors, synthesis, and methods of use Public/Granted day:2008-01-17
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