Invention Grant
- Patent Title: Acyl hydrazines as kinase inhibitors, in particular for SGK
- Patent Title (中): 酰肼作为激酶抑制剂，尤其用于SGK
-
Application No.: US11910673Application Date: 2006-03-10
-
Publication No.: US07767716B2Publication Date: 2010-08-03
- Inventor: Rolf Gericke , Dieter Dorsch , Werner Mederski , Markus Klein , Norbert Beier , Florian Lang
- Applicant: Rolf Gericke , Dieter Dorsch , Werner Mederski , Markus Klein , Norbert Beier , Florian Lang
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: DE102005015255 20050404
- International Application: PCT/EP2006/002220 WO 20060310
- International Announcement: WO2006/105850 WO 20061012
- Main IPC: C07C243/38
- IPC: C07C243/38 ; A61K31/166
Abstract:
Novel acyl hydrazides of the formula (I), in which R1-R9 have the meanings indicated in claim 1, are SGK inhibitors and can be used for the treatment of SGK-induced diseases and complaints, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in fibroses and inflammatory processes of any type.
Public/Granted literature
- US20080167380A1 Acyl Hydrazines as Kinase Inhibitors, in Particular for Sgk Public/Granted day:2008-07-10
Information query
