Invention Grant
- Patent Title: Preparation method
- Patent Title (中): 制备方法
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Application No.: US11883581Application Date: 2006-02-06
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Publication No.: US07767813B2Publication Date: 2010-08-03
- Inventor: Ilpo Laitinen , Hannele Nikander
- Applicant: Ilpo Laitinen , Hannele Nikander
- Applicant Address: FI Espoo
- Assignee: Fermion Oy
- Current Assignee: Fermion Oy
- Current Assignee Address: FI Espoo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/FI2006/000033 WO 20060206
- International Announcement: WO2006/084941 WO 20060817
- Main IPC: C07D519/00
- IPC: C07D519/00
Abstract:
The present invention is directed to a novel method for the preparation of high purity irinotecan. This can be achieved by eliminating the excess of the other reagent, bipiperidinyl-1′-carbonyl chloride after it has reacted with 7-ethyl-10-hydroxy camptothecin and crystallizing the final product from a suitable solvent.
Public/Granted literature
- US20080161572A1 Preparation Method Public/Granted day:2008-07-03
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