Invention Grant
US07767819B2 Thiazolylimidazole derivatives and their use as inhibitors of microsomal triglyceride transfer protein
失效
噻唑咪唑衍生物及其作为微粒体甘油三酯转移蛋白的抑制剂
- Patent Title: Thiazolylimidazole derivatives and their use as inhibitors of microsomal triglyceride transfer protein
- Patent Title (中): 噻唑咪唑衍生物及其作为微粒体甘油三酯转移蛋白的抑制剂
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Application No.: US10587975Application Date: 2005-01-17
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Publication No.: US07767819B2Publication Date: 2010-08-03
- Inventor: Philippe Guedat , Olivier Chevreuil , Thierry Convard
- Applicant: Philippe Guedat , Olivier Chevreuil , Thierry Convard
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: FR0401046 20040204
- International Application: PCT/EP2005/000388 WO 20050117
- International Announcement: WO2005/074934 WO 20050818
- Main IPC: C07D417/04
- IPC: C07D417/04 ; A61K31/4535
Abstract:
The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
Public/Granted literature
- US20080214610A1 Thiazolylimidazole Derivatives and Their Use as Inhibitors of Microsmal Triglyceride Transfer Protein Public/Granted day:2008-09-04
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