Invention Grant
US07767823B2 Process for the purification of a salt of clavulanic acid 有权
克拉维酸盐的纯化方法

  • Patent Title: Process for the purification of a salt of clavulanic acid
  • Patent Title (中): 克拉维酸盐的纯化方法
  • Application No.: US10275852
    Application Date: 2001-05-09
  • Publication No.: US07767823B2
    Publication Date: 2010-08-03
  • Inventor: John McKnightGuo Zhang
  • Applicant: John McKnightGuo Zhang
  • Applicant Address: GB Brentford, Middlesex
  • Assignee: SmithKline Beecham Limited
  • Current Assignee: SmithKline Beecham Limited
  • Current Assignee Address: GB Brentford, Middlesex
  • Agent Dara L. Dinner; Theodore R. Furman
  • Priority: GB0011519.6 20000513; GB0011521.2 20000513
  • International Application: PCT/GB01/02025 WO 20010509
  • International Announcement: WO01/87891 WO 20011122
  • Main IPC: C07D277/60
  • IPC: C07D277/60 C07D277/62
Process for the purification of a salt of clavulanic acid
Abstract:
A process in which a salt of clavulanic acid, typically an amine salt or an alkali metal salt is exposed to conditions, particularly a pH of less than 6.0, which reduces the quantity of contaminating impurities. The process may be a washing process, a recrystallisation process or a preparative process.
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