Invention Grant
- Patent Title: Process for the purification of a salt of clavulanic acid
- Patent Title (中): 克拉维酸盐的纯化方法
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Application No.: US10275852Application Date: 2001-05-09
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Publication No.: US07767823B2Publication Date: 2010-08-03
- Inventor: John McKnight , Guo Zhang
- Applicant: John McKnight , Guo Zhang
- Applicant Address: GB Brentford, Middlesex
- Assignee: SmithKline Beecham Limited
- Current Assignee: SmithKline Beecham Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Dara L. Dinner; Theodore R. Furman
- Priority: GB0011519.6 20000513; GB0011521.2 20000513
- International Application: PCT/GB01/02025 WO 20010509
- International Announcement: WO01/87891 WO 20011122
- Main IPC: C07D277/60
- IPC: C07D277/60 ; C07D277/62

Abstract:
A process in which a salt of clavulanic acid, typically an amine salt or an alkali metal salt is exposed to conditions, particularly a pH of less than 6.0, which reduces the quantity of contaminating impurities. The process may be a washing process, a recrystallisation process or a preparative process.
Public/Granted literature
- US20060079676A1 Process for the puritication of a salt of clavulanic acid Public/Granted day:2006-04-13
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