Invention Grant
- Patent Title: Process for the preparation of phenylcarbamates
- Patent Title (中): 苯基氨基甲酸酯的制备方法
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Application No.: US11365596Application Date: 2006-03-02
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Publication No.: US07767843B2Publication Date: 2010-08-03
- Inventor: Zhi-Xian Wang , Stephen E. Horne , K. S. Keshava Murthy
- Applicant: Zhi-Xian Wang , Stephen E. Horne , K. S. Keshava Murthy
- Applicant Address: CA Brantford
- Assignee: Apotex Pharmachem Inc.
- Current Assignee: Apotex Pharmachem Inc.
- Current Assignee Address: CA Brantford
- Main IPC: C07C269/04
- IPC: C07C269/04

Abstract:
A process for the preparation of aminoalkyl phenyl carbamate compounds of Formula I, wherein R1 and R2 independently are hydrogen or a C1-6 alkyl; R3 and R4 are the same or different and each is a C1-6 alkyl; or R3 and R4 together with the nitrogen to which they are attached form a cyclic three to eight membered ring, with or without a heteroatom like nitrogen or oxygen; R5 and R6 independently are hydrogen, linear, branched or cyclic C1-6 alkyl; or R5 and R6 together with the nitrogen to which they are attached form a cyclic three to eight membered ring, with or without a heteroatom like nitrogen or oxygen; the carbon centre designated “*” can be racemic or enantiomerically enriched in the (R)- or (S)- configuration; and pharmaceutically acceptable acid addition salts thereof.
Public/Granted literature
- US20070207990A1 Process for the preparation of phenylcarbamates Public/Granted day:2007-09-06
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