Invention Grant
- Patent Title: Process for producing optically active 2-hydroxybutyric ester
- Patent Title (中): 光学活性2-羟基丁酸酯的制备方法
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Application No.: US11994877Application Date: 2006-07-27
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Publication No.: US07767845B2Publication Date: 2010-08-03
- Inventor: Minoru Koura , Yukiyoshi Yamazaki , Kimiyuki Shibuya
- Applicant: Minoru Koura , Yukiyoshi Yamazaki , Kimiyuki Shibuya
- Applicant Address: JP Nagoya-shi
- Assignee: Kowa Co., Ltd.
- Current Assignee: Kowa Co., Ltd.
- Current Assignee Address: JP Nagoya-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2005-219163 20050728
- International Application: PCT/JP2006/314882 WO 20060727
- International Announcement: WO2007/013555 WO 20070201
- Main IPC: C07C69/66
- IPC: C07C69/66
Abstract:
A process for producing an optically active 2-hydroxybutyric ester represented by formula (1): by reacting an optically active 2,3-epoxypropionic ester represented by formula (2): with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester.
Public/Granted literature
- US20090209780A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXYBUTYRIC ESTER Public/Granted day:2009-08-20
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