Invention Grant
- Patent Title: Methods of screening agents for activity using teleosts
- Patent Title (中): 使用硬骨架筛选活动的药剂的方法
-
Application No.: US11927473Application Date: 2007-10-29
-
Publication No.: US07767880B2Publication Date: 2010-08-03
- Inventor: Patricia McGrath , Chuenlei Parng , George N. Serbedzija
- Applicant: Patricia McGrath , Chuenlei Parng , George N. Serbedzija
- Applicant Address: US MA Cambridge
- Assignee: Phylonix Pharmaceuticals, Inc.
- Current Assignee: Phylonix Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: A61K49/00
- IPC: A61K49/00 ; G01N33/00 ; A01K67/00 ; A01K67/033 ; A01K67/027

Abstract:
The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided. Methods of screening an agent for an activity in the brain or central nervous system in zebrafish are provided. The invention further provides high throughput methods of screening agents in multi-well plates.
Public/Granted literature
- US20080152591A1 Methods of Screening Agents for Activity Using Teleosts Public/Granted day:2008-06-26
Information query