An analog-to-digital (A/D) conversion device is provided and includes a first A/D conversion stage. The A/D conversion stage includes a first pre-amp unit, first and second latch units, and a first conversion unit. The first pre-amp unit amplifies the analog input data and outputs a first amplified data. The first and second latch units are enabled by first and second latch clock signals to latch the first and second amplified data and generate first and second latched data, respectively. The first pre-amp unit is reset between a time point when the first latch unit is enabled and a time point when the second latch unit is enabled. The first conversion unit receives the analog input data, and the first and second latched data and accordingly generates a first analog output data.