Clock skew may be detected measured and compensated for using phase detectors and variable delay adjusters. Phase detectors may be distributed throughout a clock distribution network and may be configured to analyze two clock signals to determine how often one signal leads the other. The output of the phase detectors may be measured and counted over a large number of clock cycles. The difference between the number of times one signal leads or lags behind the other may be used to determine the amount of delay to apply to the leading clock signal in order to minimize (reduce) skew between the two clock signals. The same techniques for detecting and measuring clock skew may also be used to detect and measure jitter in the clock signals. By configuring variable delay adjusters on clock signals, the amount of jitter in the clock signals can be measured or characterized.