发明授权
- 专利标题： Arylamino N-heteroaryl compounds as MEK inhibitors
- 专利标题（中）： 芳基氨基N-杂芳基化合物作为MEK抑制剂
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申请号： US11788028申请日： 2007-04-18
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公开(公告)号： US07772233B2公开(公告)日： 2010-08-10
- 发明人: Andreas Goutopoulos , Benny C. Askew, Jr. , Nhut Kiet Diep , Srinivasa Karra , Matthias Schwarz , Henry Yu
- 申请人： Andreas Goutopoulos , Benny C. Askew, Jr. , Nhut Kiet Diep , Srinivasa Karra , Matthias Schwarz , Henry Yu
- 申请人地址： CH Coinsins, Vaud
- 专利权人： Merck Serono, S.A.
- 当前专利权人： Merck Serono, S.A.
- 当前专利权人地址： CH Coinsins, Vaud
- 代理机构： EMD Serono, Inc.
- 代理商 Joachim Seemann
- 主分类号： C07D237/12
- IPC分类号： C07D237/12 ; C07D413/04 ; A61K31/50 ; A61K31/5355 ; A61P35/00 ; A61P29/00 ; C07D213/74 ; C07D405/12 ; C07D213/57
摘要：
The invention provides novel arylamino N-heteroaryl MEK inhibitors of Formula (I): Such compounds are MEK inhibitors that are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation. Also disclosed is the treatment of a hyperproliferative disease in mammals, and pharmaceutical compositions containing such compounds.
公开/授权文献
- US20070287709A1 Novel arylamino N-heteraryls as MEK inhibitors 公开/授权日：2007-12-13
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