A method of analyzing a lesion in a medical digital image using at least one point contained within a lesion to be analyzed includes propagating a wave-front surface from the point(s) for a plurality of steps; partitioning the wave-front surface into a plurality of wave-front parts wherein each wave-front part is associated with a different portion of the wave-front surface corresponding to a previous propagation step; and analyzing at least one feature associated with each wave-front part to classify anatomical structures associated with the lesion and normal anatomy within the medical digital image.